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Junior Research Scientist

IRBM
Roma, Lazio
1 giorno fa
Ref. 203 S

Junior Research Scientist

Peptide Chemistry Unit

IRBM is a scientific contract research organization (CRO) that stands at the forefront of drug discovery, leveraging a single, unified research facility, located in Pomezia (Rome), Italy, to accelerate team-based breakthroughs and improve efficiencies from initial concept to pre-clinical candidate.

With a history of contributing to several approved drugs, and its own internal pipeline of oncology and other therapeutic assets, IRBM is powered by deep collaborations and decades of expertise from leading global institutions. Our comprehensive in-house capabilities assist partners in achieving key milestones and progressing towards clinical readiness, positioning IRBM as a major player in driving innovation in the pharmaceutical and biotech fields.

Job Description

The peptide chemistry unit is seeking a talented chemist with a background in synthetic chemistry, preferably peptide synthesis. The candidate will be involved in the planning and execution of multi-step synthesis, purification, and analytical characterization of complex peptides to achieve agreed-upon objectives in a timely manner. Successful candidates will be passionate about conducting high-quality scientific research, communicating effectively with internal and external collaborators, and working efficiently in a multi-disciplinary team environment according to strict timelines.

Key responsibilities

    Develop and execute synthetic strategies towards complex molecules using state-of-the-art synthetic methodologies.
    Analyze and identify compounds using different purification and spectroscopic techniques.
    Present data and reports on project status at individual and group meetings.
    Conduct laboratory operations in a safe manner. Exhibit safety awareness and safe work practices; comply with all safety requirements according to Italian laws.

Competencies/skills

    Expertise in peptide chemistry for the synthesis of complex peptides, including peptide conjugates, macrocycles, and small proteins, will be preferred
    Design and execution of synthetic routes and synthesis of non-natural or special amino acids and building blocks using organic chemistry techniques
    Mastery of use of laboratory equipment with a preference for knowledge on the use of peptide synthesizers
    Knowledge of common purification techniques (HPLC, IEX, GPC) and analytical techniques (UPLC/HPLC and mass spectrometry)
    Knowledge in structure elucidations of organic molecules by NMR and MS
    Outstanding organizational skills.
    Excellent communication skills, both verbal and written
    Good knowledge of English is mandatory
    Ability to productively work in teams

Qualifications:

    Master of Science Degree (Laurea Magistrale) or PhD in Chemistry

The position is based in Pomezia (RM).

During the job interview, we will evaluate each candidate’s experience, and the job offer will be commensurate.

We thank all applicants for their interest. Only candidates selected for interviews will be contacted.

IRBM considers all qualified applicants without discrimination, including on the basis of race, gender, age, disability, gender identity or expression, national origin, religion, sexual orientation, or other protected classes. We nurture an inclusive culture where everyone can show their full potential and enjoy a fulfilling career.
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