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Scientist - Structural Characterization

Merck KGaA
Roma, Lazio
Full time
3 giorni fa

Work Your Magic with us!


Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.


United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.


Your role:
You will carry out, with limited support of the Laboratory Head, the analytical experiments aimed to the characterization of Biologics DS, DP and IPCs for development, clinical and commercial scopes work packages (e.g. comparability studies) to support non GMP and GMP testing.
With focus on glycoproteins primary, secondary, higher order structure and mass spectrometry characterization data, you will undertake the necessary management of interpretation and report of the data from experimental work for discussion with the line manager, by highlighting any atypical, critical or unusual results and proposing possible suggestions for additional experiments. Actively participate in scientific exchange initiatives within Merck and external world as well as maintains excellent collaborations with our customers.

Who you are:
  • Degree in Chemistry or Pharmaceutical Chemistry, specialization in biological characterization is a plus, desirable with 1 to 3 years of professional experience in pharmaceutical industry.
  • Excellent knowledge of the chemistry of proteins, glycoproteins, fusion proteins and related structural and physico-chemical characterization analytical methods with a focus on RP, IEX, HIC, HILIC, SEC coupled to mass spectrometry (e.g. Orbitrap, HDX, Quadrupole) and CD, FTIR, Fluorescence, DSC, DSF and characterization of aggregates and particles.
  • Successfully demonstrated expertise in Intact molecule, Primary Structure and PTMs, Glycoproteins characterization analysis.
  • Ability to work in team; Result-Oriented; Supportive and proactive; Capability to adapt to change; Eager to learn and curious.
  • Excellent knowledge of software and computer tools such as Office package, mass spectrometry data-evaluation software (e.g. Empower, BioPharmalynx, Expressionist) and attitude in digitalization;
  • Fluent spoken and written English


What we offer:
We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!


Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

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